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Ono Pharma atx inhibitor ono-8430506
At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h
Atx Inhibitor Ono 8430506, supplied by Ono Pharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/atx inhibitor ono-8430506/product/Ono Pharma
Average 90 stars, based on 1 article reviews
atx inhibitor ono-8430506 - by Bioz Stars, 2026-02
90/100 stars

Images

1) Product Images from "An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish"

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

Journal: iScience

doi: 10.1016/j.isci.2021.103254

At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h
Figure Legend Snippet: At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h

Techniques Used:

At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h
Figure Legend Snippet: At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h

Techniques Used:

The movie shows blood flow before treating the embryo with ONO-8430506
Figure Legend Snippet: The movie shows blood flow before treating the embryo with ONO-8430506

Techniques Used:

The movie shows the blood flow 20 min after treating the embryo with ONO-8430506
Figure Legend Snippet: The movie shows the blood flow 20 min after treating the embryo with ONO-8430506

Techniques Used:

At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue (vehicle control). Time-lapse images were taken for 5 min every 20 s
Figure Legend Snippet: At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue (vehicle control). Time-lapse images were taken for 5 min every 20 s

Techniques Used:

At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT (OMPT). Time-lapse images were taken for 5 min every 20 s
Figure Legend Snippet: At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT (OMPT). Time-lapse images were taken for 5 min every 20 s

Techniques Used:

At 25 hpf lpar6a +/− / lpar6b +/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s
Figure Legend Snippet: At 25 hpf lpar6a +/− / lpar6b +/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s

Techniques Used:

At 25 hpf lpar6a −/− /lpar6b −/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s
Figure Legend Snippet: At 25 hpf lpar6a −/− /lpar6b −/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s

Techniques Used:

At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with DMSO (control) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s
Figure Legend Snippet: At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with DMSO (control) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s

Techniques Used:

At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with Rockout (ROCK inhibitor) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s
Figure Legend Snippet: At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with Rockout (ROCK inhibitor) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s

Techniques Used:

Wild-type embryos were treated with ONO-8430506 (around 34 hpf) following removal of BDM. Time-lapse microscopic image was taken 2 h after the removal of BDM
Figure Legend Snippet: Wild-type embryos were treated with ONO-8430506 (around 34 hpf) following removal of BDM. Time-lapse microscopic image was taken 2 h after the removal of BDM

Techniques Used:



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Image Search Results


At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

The movie shows blood flow before treating the embryo with ONO-8430506

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: The movie shows blood flow before treating the embryo with ONO-8430506

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

The movie shows the blood flow 20 min after treating the embryo with ONO-8430506

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: The movie shows the blood flow 20 min after treating the embryo with ONO-8430506

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue (vehicle control). Time-lapse images were taken for 5 min every 20 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue (vehicle control). Time-lapse images were taken for 5 min every 20 s

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT (OMPT). Time-lapse images were taken for 5 min every 20 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT (OMPT). Time-lapse images were taken for 5 min every 20 s

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

At 25 hpf lpar6a +/− / lpar6b +/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf lpar6a +/− / lpar6b +/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

At 25 hpf lpar6a −/− /lpar6b −/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf lpar6a −/− /lpar6b −/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with DMSO (control) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with DMSO (control) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with Rockout (ROCK inhibitor) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with Rockout (ROCK inhibitor) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

Wild-type embryos were treated with ONO-8430506 (around 34 hpf) following removal of BDM. Time-lapse microscopic image was taken 2 h after the removal of BDM

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: Wild-type embryos were treated with ONO-8430506 (around 34 hpf) following removal of BDM. Time-lapse microscopic image was taken 2 h after the removal of BDM

Article Snippet: ATX inhibitor, ONO-8430506 ( ) was kindly provided from Ono Pharmaceutical Co., Ltd. ONO-8430506 was dissolved in DMSO and used at ten μM ( in vitro experiment) or 100 μM ( in vivo experiment).

Techniques:

At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques:

At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 36 hpf, wild-type embryos were treated with ONO-8430506 and time-lapse images were taken for every 30 min for 6 h

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques:

The movie shows blood flow before treating the embryo with ONO-8430506

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: The movie shows blood flow before treating the embryo with ONO-8430506

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques:

The movie shows the blood flow 20 min after treating the embryo with ONO-8430506

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: The movie shows the blood flow 20 min after treating the embryo with ONO-8430506

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques:

At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue (vehicle control). Time-lapse images were taken for 5 min every 20 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue (vehicle control). Time-lapse images were taken for 5 min every 20 s

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques:

At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT (OMPT). Time-lapse images were taken for 5 min every 20 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT (OMPT). Time-lapse images were taken for 5 min every 20 s

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques:

At 25 hpf lpar6a +/− / lpar6b +/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf lpar6a +/− / lpar6b +/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques:

At 25 hpf lpar6a −/− /lpar6b −/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf lpar6a −/− /lpar6b −/− embryos were treated with ONO-8430506 and at 36 hpf they were injected with 0.1% BSA/PBS containing 0.2% Evans blue and 1 mM OMPT. Time-lapse images were taken for 5 min every 10 s

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques:

At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with DMSO (control) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with DMSO (control) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques:

At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with Rockout (ROCK inhibitor) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: At 25 hpf wild-type embryos were treated with ONO-8430506, at 35.5 hpf were treated with Rockout (ROCK inhibitor) and at 36 hpf they were injected with 500 μM OMPT. Time-lapse images were taken for 5 min every 20 s

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques:

Wild-type embryos were treated with ONO-8430506 (around 34 hpf) following removal of BDM. Time-lapse microscopic image was taken 2 h after the removal of BDM

Journal: iScience

Article Title: An ATX-LPA 6 -Gα 13 -ROCK axis shapes and maintains caudal vein plexus in zebrafish

doi: 10.1016/j.isci.2021.103254

Figure Lengend Snippet: Wild-type embryos were treated with ONO-8430506 (around 34 hpf) following removal of BDM. Time-lapse microscopic image was taken 2 h after the removal of BDM

Article Snippet: ONO-8430506 , Ono Pharmaceutical Co., Ltd. , CAS: 1354805-08-5.

Techniques: